Chitosan/Hydroxyapatite Scaffolds with P28 as a Promising Osteoinductive Scaffold for Bone Healing Applications

Osteoinductive peptide-functionalized nanofibers with highly ordered structure as biomimetic scaffolds for bone tissue engineering

The construction of functional biomimetic scaffolds that recapitulate the topographical and biochemical features of bone tissue extracellular matrix is now of topical interest in bone tissue engineering. In this study, a novel surface-functionalized electrospun polycaprolactone (PCL) nanofiber scaffold with highly ordered structure was developed to simulate the critical features of native bone ...

Improving the mechanical and bioactivity of hydroxyapatite porous scaffold ceramic with diopside/forstrite ceramic coating

Objective(s): Scaffolds are considered as biological substitutes in bone defects which improve and accelerate the healing process of surrounding tissue. In recent years a major challenge in biomaterials is to produce porous materials with properties similar to bone tissue. In this study, the natural bioactive hydroxyapatite scaffolds with nano Diopside /Forstrite coating was successfully synthe...

Camphor as a promising insecticude for control

Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

To improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support mesenchymal stem cell (MSC) osteogenic differentiation. However, as allograft bone is derived from a wide age-range, this study aimed to determine whether donor age impacts on the abili...

benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: a review

benzofuran as an important heterocyclic compound is extensively found in natural products as well as synthetic materials. since benzofuran drivatives display a diverse array of pharmacological activities, an interest in developing new biologically active agents from benzofuran is still under consideration. this review highlights recent findings on biological activities of benzofuran derivatives...